Indikationen/Anwendungsmöglichkeiten: Warnhinweise und Vorsichtsmassnahmen: the use of a double therapy combination (diuretics, angiotensin converting enzyme inhibitors, and angiotensin receptor blockers) is not associated with an increased risk of acute kidney injury, although the risk was modified by the duration of use of a diuretic-NSAID combination. On the other hand, the use of a triple therapy combination was associated with an overall 31% higher risk, which is driven by a nearly twofold increased risk in the first 30 days of use. Overall, these results remained consistent after several sensitivity analyses (1). Referenzen: |