(Patho)physiology: the body has 3 control systems to regulate arterial blood pressure (1): - "Immediate control": the autonomic nervous system reflexes are capable of minute-to-minute control of blood pressure (1).
- "Intermediate control": renin and angiotensin (1).
- "long-term control": occurs hours after the decrease in blood pressure by altering the sodium and water balance. This process is mediated by aldosterone with the aim of restoring blood pressure to a normal level (1).
Angiotensin I is a decapeptide prohormone. Not all angiotensin I comes from conversion of angiotensinogen by renin; it is also generated by the vascular endothelium (90%) (1).
References: - Angiotensin. 5-Minute Anesthesiology Consult:Â full text.
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