Epidemiology:
- Prevalence: the rates of major bleeding (with and without bridging therapy) are 2.7% among patients with a mechanical heart valve, 2% amoug those with atrial fibrillation, and 1.9% among those with venous thromboembolism.
Procedures: low risk means <1.5% bleeding, high risk means >1.5% bleeding, or in vulnerable areas.- Anesthesiology:
- low risk:
- endotracheal intubation
- peripheral catheter placement, nontunneled catheter (peripherally inserted central catheter) placement
- high risk: spinal and epidural anesthesia (potential for profound neurologic consequences)
- Cardiac surgery:
- low risk: none
- high risk: all
- Cardiovascular:
- low risk: diagnostic coronary angiography (controversial)
- high risk:
- pacemaker or defibrillator placement (potential for profound neurologic consequences): 3.5% on warfarin therapy, 16% with bridging anticoagulation (2)
- coronary intervention
- electrophysiology testing and/or ablation
- Dental:
- low risk: tooth extraction, endodontic procedures (root canal)
- high risk: reconstructive procedures
- Dermatology:
- low risk: minor skin procedures (excision of basal and squamous cell cancers, nevi, actinic keratoses, premalignant lesions)
- high risk: major procedures (wide excision of melanoma)
- Gastroenterology:
- low risk:
- passage of endoscope for diagnostic purposes (including balloon enteroscopy) with or without mucosal biopsy
- endoscopic retrograde cholangiopancreatography without sphincterotomy
- endoscopic ultrasound without fine-needle aspiration
- nonthermal (cold) snare removal of small polyps
- lumenal self-expanding metal stent placement (controversial)
- high risk:Â
- large polypectomy (>1 cm)
- endoscopic mucosal and submucosal dissection
- biliary or pancreatic sphincterotomy
- percutaneous endoscopic gastrostomy
- endoscopic ultrasound with fine-needle aspiration or needle biopsy
- coagulation or ablation of tumors, vascular lesions
- percutaneous liver biopsy
- variceal band ligation (controversial):Â The risk of delayed bleeding following EVL (2.4 %-5.7 %) and sclerotherapy (4 %-25 %) is high (3,4).
- General surgery:
- low risk:
- suture of superficial wounds
- high risk:
- major tissue injury
- vascular organs (spleen, liver, kidney)
- bowel resection
- laparoscopy
- Gynecologic surgery:
- low risk:
- diagnostic colposcopy, hysteroscopy
- dilation and curettage, endometrial biopsy
- insertion of intrauterine device
- high risk:
- laparoscopic surgery
- bilateral tube ligation
- hysterectomy
- Interventional radiology:
- low risk:
- simple catheter exchange in well-formed, nonvascular tracts (e.g., gastrostomy, nephrostomy, cholecystostomy tubes)
- thoracentesis
- paracentesis
- aspiration of abdominal or pelvic abscesses, placement of small-caliber drains
- peripheral catheter placement, nontunneled catheter (peripherally inserted central catheter) placement
- inferior vena cava filter placement
- temporary dialysis catheter placement
- high risk:
- percutaneous transhepatic cholangiography or nephrostomy
- percutaneous drainage of liver abscess or gallbladder
- chest tube placement
- aggressive manipulation of drains or dilation of tracts
- biopsy of organs
- hickmann and tunneled dialysis catheter placement
- Intravascular procedures:
- low risk: venous access
- high risk:
- arterial puncture
- transvenous ablation
- Neurology:
- low risk: none
- high risk:
- lumbar puncture (potential for profound neurologic consequences)
- myelography
- needle electromyography (controversial)
- Neurosurgery:
- low risk: none
- high risk: intracranial, spinal surgery (potential for profound neurologic consequences)
- Ophthalmology:
- low risk:
- cataract surgery
- intraocular injections
- (Avoid retrobulbar anesthesia - controversial)
- high risk:
- periorbital surgery
- vitreoretinal surgery
- Orthopedic surgery:
- low risk: arthrocentensis
- high risk:
- joint replacement
- arthroscopy
- Otolaryngologic surgery:
- low risk:
- diagnostic fiberoptic laryngoscopy or nasopharyngoscopy, sinus endoscopy
- fine needle aspiration
- vocal cord injection
- high risk:
- any sinus surgery
- biopsy or removal of nasal polyps
- thyroidectomy
- parotidectomy
- septoplasty
- turbinate cautery
- Plastic surgery:
- low risk: injection therapy
- high risk: reconstruction
- Pulmonary:
- low risk:
- diagnostic bronchoscopy with or without bronchioalveolar lavage
- endobronchial fine-needle aspirate (controversial)
- airway stent placement (controversial)
- high risk:
- tumor ablation (laser)
- transbronchial biopsy
- stricture dilation
- Rheumatology
- low risk: arthrocentesis
- high risk: none
- Urology:
- low risk:
- circumcision
- cystoscopy without biopsy
- high risk:
- extracorporeal shock-wave lithotripsy
- transurethral prostatectomy
- bladder resection
- tumor ablation
- kidney biopsy
- Vascular surgery:
- low risk: none
- high risk:
- carotid endarterectomy
- open or endovascular aneurysm repair
- vascular bypass grafting
Downloads/links: type & screen.
References: - If not otherwise mentionned: Current Concepts: Management of Antithrombotic Therapy in Patients Undergoing Invasive Procedurs. NEJM. 2013;368(22):2113-2124: full text | pdf.
- Pacemaker or Defibrillator Surgery without Interruption of Anticoagulation. NEJM. 2013;368(22):2084-2093: full text | pdf.
- Endoscopy and antiplatelet agents. European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2011;43(5):445-461: full text.
- Incidence and management of esophageal stricture formation, ulcer bleeding, perforation, and massive hematoma formation from sclerotherapy versus band ligation. The American Journal of Gastroenterology. 2001.96;437-441: full text | pdf.
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